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LAMP1 抗体 (APC)

This anti-LAMP1 antibody is a 大鼠 单克隆 antibody detecting LAMP1 in FACS. Suitable for 小鼠.
产品编号 ABIN371197
发货至: 中国

Quick Overview for LAMP1 抗体 (APC) (ABIN371197)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This LAMP1 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

1D4B
  • 特异性

    This antibody is specific to CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa).

    产品特性

    Synonyms: LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1, CD107Antigen-like Family Member A

    免疫原

    Plasma membrane fraction of mouse embryo NIH3T3 cell line. (Ref. 1)

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.5)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a / LAMP1

    背景

    CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. (Ref.2) CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.3) LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. (Ref.4)Synonyms: CD107 Antigen-like Family Member A, LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1

    基因ID

    16783

    UniProt

    P11438

    途径

    Autophagy
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